Thursday , February 9 2023

Increased blood vessel blood failure at UBC could affect diabetes, Alzheimer's research – BC


UBC scientists have made a breakthrough in cardiovascular research that could have major effects in people with diseases such as diabetes.

For the first time, scientists have successfully grown human blood vessels that are perfect as organisms in a petri dish.

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The technique, highlighted in a new study in the journal The nature on Wednesday, could allow doctors to prevent future blood vessel changes, one of the leading causes of death among people with diabetes.

Organoids are three-dimensional structures made up of stem cells that mimic an organ and can be used to study aspects of that organ.

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Each organ in our body is linked to the circulatory system, study author Josef Penninger said.

This could allow researchers to discover the causes and treatments for a variety of vascular diseases, from Alzheimer's disease, cardiovascular disease, wound healing problems, stroke, cancer and, of course, diabetes.

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Researchers used stem cells to grow organoids from three-dimensional human blood vessels in a laboratory. They then transplanted organoids into mice, where they developed into fully human blood vessels.

Researchers said the study shows that not only can organs of blood vessels be raised from stem cells in a laboratory but that a human vascular system can be grown in a non-human species.

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