Thursday , June 1 2023

Urban Urban – UOH Researcher was awarded the Chilean Endocrinology and Diabetes Research Project


Additionally, Dr. Paulina Ormazábal, of the Institute of Health Sciences, presented some preliminary results corresponding to this new research line at the XXIX SOCHED Congress which took place at Coquimbo.

Dr. Paulina Ormazábal, Institute of Health Scientists (ICS), received funding from the Chilean Society for Endocrinology and Diabetes (SOCHED), which aims to promote the development of clinical, clinical or clinical epidemiological research into endocrinology and diabetes, which can serve as a basis for study lines or more advanced projects in the future.

Dr. Ormazábal has applied to the project the project "Effect of the Plant Lampaya Medicinalis Phil. on the activation of JNK and fatty acid-induced TNF-α and FABP4 levels in human hepatocites HEPG2 ", which constitutes a new branch of the UOH Academy's research on the beneficial effect of the endemic plant in Chile's mountainous areas , Lampaya Medicinalis, against inflammation induced by fatty acids in liver cells.

"With these funds I will be able to choose to evaluate new molecular markers of inflammation by more specific and more sensitive laboratory techniques," Dr. Ormazábal explained.

Regarding the importance of granting this fund, the researcher said that "it is an acknowledgment of the research work carried out within the UOH." This paper aims at validating the ethno-pharmacological knowledge of the use of medicinal plants for the treatment of diseases. will study a phenomenon that occurs frequently in obesity and which corresponds to inflammation of the liver due to the accumulation of fat inside the liver cell. The above are transcendental when overweight and obesity are conditions with high prevalence at national and global level, and sins, our region does not escape this reality. "

Verifies from the scientific point of view that Lampaya Medicinalis It has an anti-inflammatory effect, will have a strong local and national impact because it is a native Chilean plant, being able to design its use as complementary therapy for the treatment of inflammatory liver phenomena associated with overweight and obesity.

During the first five days of the SOCHED Congress

In addition, Dr. Ormazábal presented preliminary results for this new research line at the XXIX SOCHED Congress that took place in Coquimbo municipality from November 8-10.

The title of the paper presented at the Congress was "Effect of the hydroalcoholic extract of andine plant Lampaya on in vitro induced steatoatomy in human hepatocytes "

On this occasion, the paper was selected among the top five in translational endocrinology.

This research is the product of the multidisciplinary work of chemists, biologists and biochemists. Extract from Lampaya Medicinalis It is prepared and donated by the researchers of the Biological Chemistry Laboratory of the Antofagasta Institute at the University of Antofagasta, and the experiments are performed in INTA's Laboratory of Obesity, Metabolism and Aging.

It should be noted that in October this year, ICS academician received the SOCHINUT – Henri Nestlé 2018 Award for the Scientific Development Fund, which aims to provide support and visibility to researchers who, thanks to their active and innovative work, contribute to improving the quality of Chilean life in the field of nutrition, nutrition and health – through their research project "The Effect of Plant Protection Lampaya medicinalis Phil on steatosis and fatty acid-induced liver inflammation in human hepatocites HEPG2".

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