If the adolescent or young adult child is obese, he or she may be at four times more likely to develop pancreatic cancer later in life, say new researchers.
Tel Aviv University researchers analyzed 1,087,358 Jewish men and 707,212 women between 16 and 19 for the study published in the Cancer journal.
It has shown that overweight and even greater weight in the "normal" weight range in men may increase the risk of pancreatic cancer in a gradual fashion.
Compared to normal weight, obesity was associated with a 3.67-fold higher risk of cancer among men and a 4.07-fold higher risk among women, the report said.
In addition, high-grade BMI and overweight men were associated with 49% and 97% higher risk for cancer compared to those with low BMI.
Pancreatic cancer is the sixth most common cause of cancer-related deaths in the world and adult obesity has been linked to an increased risk of it occurring.
It has an extremely low survival rate that has only improved over the last 40 years.
The combination of complex, biological, bio-mechanical and structural chemical factors found in pancreatic cancer tissues makes treatment difficult.
Systemic inflammation caused by obesity is a potential engine for the development of pancreatic cancer. Thus, weight management could help reduce the risk, the researchers have noted.
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